The creator of the hit sitcom The Big Bang Theory, Chuck Lorre has filed for divorce from his wife Arielle Lorre, 36, marking the end of his third marriage.

The 69-year-old TV sitcom guru married his third wife in October 2018. The Court documents obtained by TMZ revealed that the pair had separated in May 2022 and Chuck Lorre had cited irreconcilable differences as the reason for the divorce.

“It is with mutual consideration and respect that we have decided to separate. Our plan is to move forward in different directions but with great love, admiration, and gratitude for the time we shared. We ask that you respect our privacy during this difficult time. Thank you for your support,” the statement said.

The pair had signed a pre-nuptial agreement before their wedding. The agreement also indicates he will pay spousal support and attorney fees as well.

Arielle is well-known as a health and wellness brand and is the host of the podcast The Blonde Flies by Dear Media Studios.

Although the former couple did not have any children together, the producer has two adult children from his first marriage to Paula Smith. He was married to Smith from 1979 to 1992 and to his second wife Karen Witter, who is an actress, and writer, from 2001 to 2010.

Aside from The Big Bang Theory, he is the creator of Two And A Half Men, his other sitcom credits are Dharma & Greg, Mom, Mike and Molly, and Cybill. He earned Emmy nominations for his NetFlix comedy series The Kominsky Method.